Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 18/20 | 0.48 |
| ▸ | CTSD | P07339 | 16/20 | 0.48 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL13685475 | 1.00 | BACE1 (0.48) | BACE1CTSDBACE2REN | |
| Formic Acid SCHEMBL2286944 | 0.87 | BACE1 (0.56) | BACE1CTSD | |
| Formic Acid SCHEMBL2286466 | 0.87 | BACE1 (0.54) | BACE1CTSDBACE2 | |
| Formic Acid SCHEMBL2284430 | 0.85 | BACE1 (0.63) | BACE1CTSD | |
| Formic Acid SCHEMBL2285584 | 0.84 | BACE1 (0.58) | BACE1CTSDBACE2REN | |
| Formic Acid SCHEMBL2285183 | 0.82 | BACE1 (0.53) | BACE1CTSDBACE2REN | |
| SCHEMBL2281795 | 0.82 | BACE1 (0.58) | BACE1CTSDBACE2 | |
| SCHEMBL2281803 | 0.82 | BACE1 (0.58) | BACE1CTSDBACE2 | |
| SCHEMBL2284420 | 0.81 | BACE1 (0.61) | BACE1CTSD | |
| SCHEMBL2284415 | 0.81 | BACE1 (0.61) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245019-B1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-11-14 | — | — | EP | disclosed |