Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 14/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1473750 | 1.00 | KCNA5 (0.40) | KCNA5TRPV1KIF11 | |
| SCHEMBL12827340 | 1.00 | KCNA5 (0.40) | KCNA5TRPV1KIF11 | |
| SCHEMBL12747845 | 1.00 | KCNA5 (0.40) | KCNA5TRPV1KIF11 | |
| SCHEMBL1474073 | 0.91 | TRPV1 (0.39) | KCNA5TRPV1 | |
| SCHEMBL12747970 | 0.89 | TRPV1 (0.39) | TRPV1KIF11 | |
| SCHEMBL1473733 | 0.89 | TRPV1 (0.39) | TRPV1KIF11 | |
| SCHEMBL1474213 | 0.89 | TRPV1 (0.39) | TRPV1KIF11 | |
| SCHEMBL13685635 | 0.89 | TRPV1 (0.39) | TRPV1KIF11 | |
| SCHEMBL1474715 | 0.87 | KIF11 (0.43) | KCNA5KIF11 | |
| SCHEMBL12827633 | 0.87 | KIF11 (0.43) | KCNA5KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861359-B1 | N-(N-SULFONYLAMINOMETHYL)CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | PFIZER (US) | 2012-11-14 | — | — | EP | claimed |