Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN2 | P17655 | 9/20 | 0.34 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.32 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.32 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.32 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.32 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.32 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.32 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.32 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.32 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.32 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.32 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.32 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13685753 | 1.00 | CAPN2 (0.34) | CAPN2PSMB11PSMA7CAPN1CTSB | |
| SCHEMBL13685652 | 0.93 | CAPN2 (0.34) | CAPN2PSMB11PSMA7CAPN1CTSB | |
| SCHEMBL13685694 | 0.90 | CAPN2 (0.38) | CAPN2PSMB11PSMA7CAPN1CTSB | |
| SCHEMBL13685734 | 0.87 | TERF2 (0.32) | TERF2 | |
| SCHEMBL13685653 | 0.83 | CAPN2 (0.38) | CAPN2PSMB11PSMA7CAPN1CTSB | |
| SCHEMBL13685773 | 0.81 | TERF2 (0.33) | TERF2 | |
| SCHEMBL13685681 | 0.78 | TERF2 (0.34) | TERF2 | |
| SCHEMBL13685735 | 0.71 | TERF2 (0.37) | TERF2 | |
| SCHEMBL13685689 | 0.71 | TERF2 (0.34) | TERF2 | |
| SCHEMBL13685682 | 0.71 | TERF2 (0.36) | TERF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592419-B2 | Macrocyclic inhibitors of hepatitis C virus NS3-serine protease | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |