SCHEMBL1368705

SCHEMBL1368705

C=C(C)C(=O)OC(F)(F)C(F)(F)C(F)CF

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.33
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3917219 0.86 TSHR (0.35) TSHRALDH1A1THRB
SCHEMBL36678 0.85 TSHR (0.34) TSHRALDH1A1
SCHEMBL9313746 0.83 ALDH1A1 (0.35) TSHRALDH1A1THRB
SCHEMBL1449199 0.82 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL28712395 0.81 TSHR (0.32) TSHR
SCHEMBL2784741 0.80 TSHR (0.38) TSHRALDH1A1
SCHEMBL9304235 0.80 TSHR (0.41) TSHR
SCHEMBL8022199 0.80 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL9617554 0.79 ALDH1A1 (0.35) TSHRALDH1A1
SCHEMBL17159429 0.79 TSHR (0.30) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115023474-A Primer and finish paint 贝洱工艺公司 2022-09-06 CN claimed
CN-111836839-A Antimicrobial contact lenses 克拉梅德有限公司 2020-10-27 CN claimed
CN-110753859-A Cytostatic copolymers for use in ophthalmic implants 伊齐耶·舒埃 2020-02-04 CN claimed
US-10273377-B2 Superhydrophobic and oleophobic ceramic polymer composite coating UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2019-04-30 US claimed
EP-2316500-B1 Methacrylate copolymers for medical devices ABBOTT CARDIOVASCULAR SYSTEMS (US) 2016-05-11 EP claimed
EP-2316500-A1 Methacrylate copolymers for medical devices Abbott Cardiovascular Systems Inc. (US) 2011-05-04 EP claimed
US-11807728-B2 Fluorine-containing polycaprolactone film and preparation method therefor SOOCHOW UNIVERSITY (CN) 2023-11-07 US disclosed
CN-116940640-A Scratch-resistant and abrasion-resistant coating formulation 贝洱工艺公司 2023-10-24 CN disclosed
CN-115023474-A Primer and finish paint 贝洱工艺公司 2022-09-06 CN disclosed
CN-110577648-B Preparation method of hydrophobic polycaprolactone 苏州大学 2021-09-28 CN disclosed
US-20210079184-A1 FLUORINE-CONTAINING POLYCAPROLACTONE FILM AND PREPARATION METHOD THEREFOR SOOCHOW UNIVERSITY (CN) 2021-03-18 US disclosed
CN-108611861-B Super-hydrophobic microsphere, preparation method thereof and super-hydrophobic fabric prepared from microsphere 苏州大学 2020-11-17 CN disclosed
CN-111836839-A Antimicrobial contact lenses 克拉梅德有限公司 2020-10-27 CN disclosed
EP-2574966-A2 Optical element and method for manufacturing the same Canon Kabushiki Kaisha (JP) 2013-04-03 EP disclosed
US-20120231379-A1 FLUORINE-CONTAINING RESIN PARTICLE DISPERSION, METHOD FOR PREPARING FLUORINE-CONTAINING RESIN PARTICLE DISPERSION, COATING LIQUID WHICH CONTAINS FLUORINE-CONTAINING RESIN PARTICLES, METHOD FOR PREPARING COATING FILM WHICH CONTAINS FLUORINE-CONTAINING RESIN PARTICLES, COATING FILM WHICH CONTAINS FLUORINE-CONTAINING RESIN PARTICLES, MOLDED BODY, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR PREPARING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-09-13 US disclosed
CN-102300545-A Dental filling repair kit 2011-12-28 CN disclosed
US-20110288195-A1 DENTAL FILLING/RESTORATION KIT TOKUYAMA DENTAL CORPORATION (JP) 2011-11-24 US disclosed
EP-1723181-A4 TELECHELIC POLYMERS CONTAINING REACTIVE FUNCTIONAL GROUPS PENN STATE RES FOUND (US) 2009-01-21 EP disclosed
EP-1723181-A1 TELECHELIC POLYMERS CONTAINING REACTIVE FUNCTIONAL GROUPS THE PENN STATE RESEARCH FOUNDATION (US) 2006-11-22 EP disclosed
WO-2005085297-A1 TELECHELIC POLYMERS CONTAINING REACTIVE FUNCTIONAL GROUPS PENN STATE RESEARCH FOUNDATION (US) 2005-09-15 WO disclosed