Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | CD74 | P04233 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2969446 | 0.92 | CTSS (0.51) | CTSSKCNK3CD74 | |
| SCHEMBL13687516 | 0.84 | CTSS (0.72) | CTSSCD74 | |
| SCHEMBL2974056 | 0.80 | CTSS (0.65) | CTSSKCNK3CREBBP | |
| SCHEMBL2983881 | 0.79 | CTSS (0.71) | CTSSKCNK3CREBBP | |
| SCHEMBL2972734 | 0.78 | CTSS (0.61) | CTSSKCNK3CREBBP | |
| SCHEMBL2981273 | 0.77 | CTSS (0.69) | CTSSKCNK3CREBBP | |
| SCHEMBL8408387 | 0.76 | CTSS (0.76) | CTSSCD74 | |
| SCHEMBL14015780 | 0.75 | CTSS (0.83) | CTSSKCNK3CD74 | |
| SCHEMBL13687436 | 0.75 | CTSS (0.71) | CTSSKCNK3CREBBPCD74 | |
| SCHEMBL2969850 | 0.75 | CTSS (0.88) | CTSSCD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589202-B2 | Substituted pyrazoles | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2009-09-15 | — | — | US | disclosed |
| US-7393850-B2 | Substituted pyrazoles | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2008-07-01 | — | — | US | disclosed |