SCHEMBL136884

SCHEMBL136884

C1=CC(C(C2C=Cc3ccccc32)(C2C=Cc3ccccc32)C2C=Cc3ccccc32)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.40
HTR6 P50406 1/20 0.39
SIGMAR1 Q99720 6/20 0.33
KDM4E B2RXH2 2/20 0.32
CYP2D6 P10635 2/20 0.32
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1030004 0.82 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ECYP2D6
SCHEMBL28418270 0.82 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ECYP2D6
SCHEMBL1452608 0.82 HTR6 (0.41) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Lithium SCHEMBL5702700 0.80 HTR6 (0.40) HTR2AHTR6SIGMAR1KDM4ECYP2D6
SCHEMBL9145153 0.80 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4ECYP2D6
SCHEMBL5702695 0.80 HTR6 (0.40) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Lithium SCHEMBL9145158 0.80 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4ECYP2D6
SCHEMBL9144761 0.80 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4ECYP2D6
SCHEMBL9144758 0.80 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4ECYP2D6
SCHEMBL8971418 0.79 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4ECYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3227384-B1 VULCANIZABLE RUBBER COMPOSITION Arlanxeo Netherlands Bv (NL) 2019-02-20 EP claimed
US-10150859-B2 Vulcanizable rubber composition ARLANXEO NETHERLANDS B.V. (NL) 2018-12-11 US claimed
US-20170313868-A1 VULCANIZABLE RUBBER COMPOSITION ARLANXEO NETHERLANDS B.V. (NL) 2017-11-02 US claimed
EP-3227384-A1 VULCANIZABLE RUBBER COMPOSITION Arlanxeo Netherlands B.V. (NL) 2017-10-11 EP claimed
WO-2016087647-A1 VULCANIZABLE RUBBER COMPOSITION LANXESS ELASTOMERS B.V. (NL) 2016-06-09 WO claimed
EP-3029102-A1 Vulcanizable rubber composition Lanxess Elastomers B.V. (NL) 2016-06-08 EP claimed
EP-2818513-B1 Oil extended ethylene-alpha-olefin-non-conjugated diene copolymer LANXESS ELASTOMERS BV (NL) 2015-12-23 EP claimed
EP-2818513-A1 Oil extended ethylene-alpha-olefin-non-conjugated diene copolymer Lanxess Elastomers B.V. (NL) 2014-12-31 EP claimed
WO-2014206952-A1 OIL EXTENDED ETHYLENE-ALPHA-OLEFIN-NON-CONJUGATED DIENE COPOLYMER LANXESS ELASTOMERS B.V. (NL) 2014-12-31 WO claimed
US-4966940-A Vulcanized, ethylene/alpha-olefin copolymer rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-30 US claimed
EP-0346837-A2 Vulcanized, ethylene/alpha-olefin copolymer rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-12-20 EP claimed
CN-118221861-A Polyolefin copolymers, curable compositions and articles comprising the same, and uses thereof 阿朗新科高性能弹性体(常州)有限公司 2024-06-21 CN disclosed
CN-118221860-A Polyolefin copolymer, rubber composition comprising same, curable composition and article and use thereof 阿朗新科高性能弹性体(常州)有限公司 2024-06-21 CN disclosed
CN-116249738-A Article having a crosslinked foam layer adhered to a substrate 陶氏环球技术有限责任公司 2023-06-09 CN disclosed
US-20210002443-A1 RUBBER SPONGE AND FOAMABLE RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-01-07 US disclosed
US-20020055547-A1 Process for producing foamed rubber SUMITOMO CHEMICAL COMPANY, LIMITED 2002-05-09 US disclosed
US-6384290-B1 ETHYLENE-ALPHA-OLEFIN NONCONJUGATED DIENE TERPOLYMERS AND EXTENDER OIL THAT PROVIDES EXCELLENT LONG-TERM COMPRESSION, SEALING, LOW-TEMPERATURE PROPERTIES, PROCESSABILITY AND APPEARANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2002-05-07 US disclosed
CN-1316453-A Foamed rubber, its preparation method and composite containing the foamed rubber SUMITOMO CHEMICAL CO (JP) 2001-10-10 CN disclosed
US-20010021449-A1 Foamed rubber, process for producing the same and composite comprising the foamed rubber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-13 US disclosed
EP-0816422-A1 Flame retardant resin composition and molded article thereof SHOWA DENKO KABUSHIKI KAISHA (JP) 1998-01-07 EP disclosed