Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 5/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17037424 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL17037425 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL20798910 | 0.84 | METAP1 (0.39) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL9051943 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL3088751 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL20366038 | 0.81 | MME (0.46) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL26291258 | 0.80 | DPP4 (0.44) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL8819205 | 0.80 | DPP4 (0.44) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL19853267 | 0.79 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL17037466 | 0.79 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106982-A1 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |