Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 11/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 11/20 | 0.55 |
| ▸ | ITGB7 | P26010 | 9/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13693097 | 0.92 | ITGB1 (0.46) | ITGB1ITGA4ITGB7OPRM1OPRK1 | |
| SCHEMBL13602001 | 0.88 | ITGB1 (0.66) | ITGB1ITGA4ITGB7OPRM1OPRK1 | |
| SCHEMBL13693055 | 0.79 | ITGB1 (0.54) | ITGB1ITGA4ITGB7OPRM1OPRK1 | |
| SCHEMBL6807415 | 0.73 | ITGA4 (0.50) | ITGB1ITGA4ITGB7OPRM1OPRK1 | |
| SCHEMBL11750694 | 0.73 | ITGB1 (0.72) | ITGB1ITGA4ITGB7ITGB3ITGAV | |
| SCHEMBL6807468 | 0.72 | ITGB1 (0.54) | ITGB1ITGA4ITGB7 | |
| SCHEMBL13601993 | 0.71 | ITGB1 (0.84) | ITGB1ITGA4ITGB7ITGB3ITGAV | |
| SCHEMBL8278642 | 0.71 | ITGA4 (0.79) | ITGB1ITGA4ITGB7ITGB3ITGAV | |
| SCHEMBL13601965 | 0.71 | ITGB1 (1.00) | ITGB1ITGA4ITGB7ITGB3ITGAV | |
| SCHEMBL13602006 | 0.71 | ITGB1 (0.79) | ITGB1ITGA4ITGB7ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595399-B2 | Tyrosine derivatives | GENENTECH, INC. (US) | 2009-09-29 | — | — | US | disclosed |