Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.71 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.71 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | PI4KA | P42356 | 1/20 | 0.64 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.64 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.64 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.64 |
| ▸ | AHCY | P23526 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13901807 | 1.00 | ADORA3 (0.71) | ADORA3ADORA2ATSHRADORA2BADORA1 | |
| SCHEMBL22354945 | 0.89 | ADORA3 (0.60) | ADORA3ADORA2ATSHRADORA2BADORA1 | |
| SCHEMBL22332144 | 0.89 | ADORA3 (0.69) | ADORA3ADORA2ATSHRADORA2BADORA1 | |
| SCHEMBL20925712 | 0.89 | ADORA3 (0.69) | ADORA3ADORA2ATSHRADORA2BADORA1 | |
| SCHEMBL20925696 | 0.89 | ADORA3 (0.69) | ADORA3ADORA2ATSHRADORA2BADORA1 | |
| SCHEMBL29417473 | 0.88 | PI4KA (0.59) | ADORA3ADORA2ATSHRADORA2BADORA1 | |
| SCHEMBL22354943 | 0.88 | PI4KA (0.59) | ADORA3ADORA2ATSHRADORA2BADORA1 | |
| SCHEMBL22342582 | 0.88 | PI4KA (0.59) | ADORA3ADORA2ATSHRADORA2BADORA1 | |
| SCHEMBL22354823 | 0.88 | PI4KA (0.69) | ADORA3ADORA2ATSHRADORA2BADORA1 | |
| SCHEMBL17297709 | 0.87 | PI4KA (0.58) | ADORA3ADORA2ATSHRADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233878-A1 | NOVEL ADENOSINE A3 RECEPTOR AGONISTS | CREDIT SUISSE AG | 2009-09-17 | — | — | US | disclosed |
| US-20090233878-A1 | NOVEL ADENOSINE A3 RECEPTOR AGONISTS | CREDIT SUISSE AG | 2009-09-17 | — | — | US | disclosed |
| US-7511133-B2 | Adenosine A3 receptor agonists | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-7511133-B2 | Adenosine A3 receptor agonists | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2009-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233878-A1 | NOVEL ADENOSINE A3 RECEPTOR AGONISTS | ADORA3, ADORA1, ADORA2A | ADORA3 1/4885ADORA2A 3/4885TSHR 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.