Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13602316 | 0.89 | ALDH1A1 (0.64) | ALDH1A1MAPTPOLBKDM4ECYP1A2 | |
| SCHEMBL5391256 | 0.85 | MEN1 (0.69) | ALDH1A1MAPTPOLBKDM4ECYP1A2 | |
| SCHEMBL11175842 | 0.82 | POLB (0.72) | ALDH1A1MAPTPOLBKDM4ECYP1A2 | |
| SCHEMBL30063430 | 0.82 | POLB (0.72) | ALDH1A1MAPTPOLBKDM4ECYP1A2 | |
| SCHEMBL2490151 | 0.81 | POLB (0.67) | ALDH1A1MAPTPOLBKDM4ECYP1A2 | |
| SCHEMBL29739503 | 0.81 | POLB (0.67) | ALDH1A1MAPTPOLBKDM4ECYP1A2 | |
| SCHEMBL7088771 | 0.80 | GAA (0.62) | ALDH1A1MAPTPOLBKDM4ECYP1A2 | |
| SCHEMBL13690001 | 0.78 | KMT2A (0.52) | ALDH1A1MAPTPOLBCYP1A2MEN1 | |
| SCHEMBL11131058 | 0.78 | POLB (0.63) | ALDH1A1MAPTPOLBKDM4ECYP1A2 | |
| SCHEMBL61187 | 0.78 | POLB (0.71) | ALDH1A1MAPTPOLBKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595399-B2 | Tyrosine derivatives | GENENTECH, INC. (US) | 2009-09-29 | — | — | US | disclosed |