Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 20/20 | 0.67 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1689755 | 0.92 | LTB4R (0.78) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL13690350 | 0.89 | LTB4R (0.83) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL310090 | 0.85 | LTB4R (0.65) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL13690365 | 0.84 | LTB4R (0.85) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL13690235 | 0.81 | LTB4R (0.68) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL1689881 | 0.81 | LTB4R (1.00) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL10165267 | 0.79 | LTB4R (0.58) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL1689655 | 0.79 | LTB4R (1.00) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL1689706 | 0.78 | LTB4R (0.90) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL1689778 | 0.77 | LTB4R (0.81) | LTB4RLTB4R2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109483-A1 | LEUKOTRIENE B4 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-11 | — | — | WO | disclosed |