Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 20/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690253 | 0.94 | LTB4R (0.51) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL310064 | 0.92 | LTB4R (0.56) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL13690294 | 0.92 | LTB4R (0.49) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL13174996 | 0.90 | LTB4R (0.56) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL309284 | 0.90 | LTB4R (0.54) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL13690247 | 0.89 | LTB4R (0.66) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL309511 | 0.88 | LTB4R (0.66) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL309248 | 0.87 | LTB4R (0.67) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL202321 | 0.87 | LTB4R (0.56) | LTB4RLTB4R2CYP2C9 | |
| SCHEMBL13690368 | 0.87 | LTB4R (0.51) | LTB4RLTB4R2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109483-A1 | LEUKOTRIENE B4 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-11 | — | — | WO | disclosed |