Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | STK10 | O94804 | 2/20 | 0.37 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972411 | 0.84 | ABL1 (0.53) | ARBACE1ABL1ABCB1BCR | |
| SCHEMBL1027860 | 0.74 | SCN9A (0.53) | ARBACE1TRPA1STK10SLK | |
| SCHEMBL308936 | 0.74 | NR1H2 (0.43) | ARTRPA1 | |
| SCHEMBL1513543 | 0.71 | AR (0.50) | ARBACE1ABL1ABCB1BCR | |
| SCHEMBL22304414 | 0.68 | AR (0.58) | ARBACE1TRPA1FFAR4ALDH1A1 | |
| SCHEMBL29630556 | 0.68 | ALDH1A1 (0.51) | ARFFAR4ALDH1A1HPGDSCN9A | |
| SCHEMBL28972663 | 0.68 | ABL1 (0.43) | ARABL1ABCB1BCRSTK10 | |
| SCHEMBL24017164 | 0.68 | AR (0.50) | ARBACE1TRPA1FFAR4SCN9A | |
| SCHEMBL24017176 | 0.68 | AR (0.50) | ARBACE1TRPA1FFAR4ALDH1A1 | |
| SCHEMBL23934168 | 0.68 | AR (0.50) | ARBACE1TRPA1ALDH1A1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109483-A1 | LEUKOTRIENE B4 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-11 | — | — | WO | disclosed |