Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 0.78 |
| ▸ | TSHR | P16473 | 3/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | AURKA | O14965 | 2/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13692561 | 0.89 | MAPT (0.84) | MAPTALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL13692553 | 0.88 | KDM4E (1.00) | MAPTALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL13692557 | 0.87 | MAPT (0.81) | MAPTALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL13692556 | 0.86 | KDM4E (0.80) | MAPTALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL13692640 | 0.85 | KDM4E (1.00) | MAPTALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL13692562 | 0.85 | MAPT (0.77) | MAPTALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL13692567 | 0.84 | KDM4E (0.82) | MAPTALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL13692671 | 0.83 | KDM4E (0.81) | MAPTALDH1A1KDM4ENPSR1HPGD | |
| Hydrochloric Acid SCHEMBL11242122 | 0.82 | MAPT (0.75) | MAPTALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL13692560 | 0.82 | MAPT (0.79) | MAPTALDH1A1KDM4ENPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221624-A1 | 4-AMINOQUINOLINE COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | OLIVO PAUL D | 2009-09-03 | — | — | US | disclosed |
| US-20090221624-A1 | 4-AMINOQUINOLINE COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | OLIVO PAUL D | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221624-A1 | 4-AMINOQUINOLINE COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | MAVS, EIF2AK2, SARS1 | MAPT 1032/4885ALDH1A1 1687/4885KDM4E 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.