⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rhodanine SCHEMBL55625 | 0.97 | — | — | |
| Rhodanine SCHEMBL94126 | 0.97 | — | — | |
| Rhodanine SCHEMBL2229918 | 0.97 | GSK3A (1.00) | — | |
| Rhodanine SCHEMBL13740442 | 0.95 | — | — | |
| Rhodanine SCHEMBL5511180 | 0.95 | — | — | |
| Rhodanine SCHEMBL1461756 | 0.95 | — | — | |
| Rhodanine SCHEMBL11436580 | 0.95 | — | — | |
| Rhodanine SCHEMBL8017015 | 0.95 | — | — | |
| Rhodanine SCHEMBL5919491 | 0.95 | — | — | |
| Rhodanine SCHEMBL2403229 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194306-A1 | COMPOSITIONS FOR DIAGNOSIS AND THERAPY OF DISEASES ASSOCIATED WITH ABERRANT EXPRESSION OF FUTRINS (R-SPONDINS) AND/OR WNT | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2019-06-27 | — | — | US | disclosed |
| US-20160376349-A1 | Compositions For diagnosis and Therapy of diseases associated with aberrant expression of Futrins (R-Spondins) and/or Wnt | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2016-12-29 | — | — | US | disclosed |
| US-9081011-B2 | Compositions for diagnosis and therapy of diseases associated with aberrant expression of futrins (R-spondins) and/or Wnt | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2015-07-14 | — | — | US | disclosed |
| US-8951745-B2 | Compositions for diagnosis and therapy of diseases associated with aberrant expression of futrins (R-Spondins) and/or Wnt | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2015-02-10 | — | — | US | disclosed |
| US-8921056-B2 | Compositions for diagnosis and therapy of diseases associated with aberrant expression of futrins (R-Spondins) and/or Wnt | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2014-12-30 | — | — | US | disclosed |
| US-20140357510-A1 | Compositions for Diagnosis and Therapy of Diseases Associated with Aberrant Expression of Futrins (R-Spondins) and/or Wnt | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2014-12-04 | — | — | US | disclosed |
| US-20140227713-A1 | Compositions for Diagnosis and Therapy of Diseases Associated with Aberrant Expression of Futrins (R-Spondins) and/or Wnt | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140186917-A1 | Compositions for Diagnosis and Therapy of Diseases Associated with Aberrant Expression of Futrins (R-Spondins) and/or Wnt | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2014-07-03 | — | — | US | disclosed |
| US-20140134703-A1 | Compositions for Diagnosis and Therapy of Diseases Associated with Aberrant Expression of Futrins (R-Spondins) and/or Wnt | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2014-05-15 | — | — | US | disclosed |
| US-20130337533-A1 | Compositions for Diagnosis and Therapy of Diseases Associated with Aberrant Expression of Futrins (R-Spondins) and/or Wnt | DEUTSCHES KREBSFORSCH (DE) | 2013-12-19 | — | — | US | disclosed |
| WO-2004067560-A2 | HERPES SIMPLEX VP16 PROTEIN BINDING POLYPEPTIDES | GSF - FORSCHUNGSZENTRUM FÜR UMWELT UND GESUNDHEIT, GMBH (DE) | 2004-08-12 | — | — | WO | disclosed |
| US-20040072998-A1 | Trp8, trp9 and trp10, novel markers for cancer | WISSENBACH ULRICH (DE) | 2004-04-15 | — | — | US | disclosed |
| WO-2003104489-A2 | MCHR1 VARIANT ASSOCIATED WITH HUMAN OBESITY | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2003-12-18 | — | — | WO | disclosed |
| EP-1366158-A2 | TRP8, TRP9 AND TRP10, MARKERS FOR CANCER | Wissenbach, Ulrich (DE) | 2003-12-03 | — | — | EP | disclosed |
| WO-2003087818-A2 | DIAGNOSTIC AND THERAPEUTIC USE OF KREMEN 1 AND 2, INHIBITORS OF THE CANONICAL WNT-SIGNALTRANSDUCTION | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2003-10-23 | — | — | WO | disclosed |
| EP-1355152-A1 | Compositions for diagnosis and therapy of diseases associated with aberrant expression of kremen | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2003-10-22 | — | — | EP | disclosed |
| WO-2003078458-A2 | TAP-70, A NOVEL MARKER FOR EPITHELIAL TUMORS | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2003-09-25 | — | — | WO | disclosed |
| EP-1347054-A1 | TAP-70, a novel marker for epithelial tumors | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002010382-A9 | TRP8, TRP9 AND TRP10, MARKERS FOR CANCER | WISSENBACH ULRICH (DE) | 2002-09-19 | — | — | WO | disclosed |
| WO-2002010382-A2 | TRP8, TRP9 AND TRP10, MARKERS FOR CANCER | WISSENBACH ULRICH (DE) | 2002-02-07 | — | — | WO | disclosed |