SCHEMBL13692802

SCHEMBL13692802

Ic1ccc(Oc2ccc(C(c3ccc(Oc4ccc(I)cc4)cc3)(c3ccc(Oc4ccc(I)cc4)cc3)c3ccc(Oc4ccc(I)cc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 0.46
NPC1 O15118 2/20 0.45
MAPT P10636 2/20 0.45
RAB9A P51151 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 1/20 0.45
MAPK1 P28482 1/20 0.45
LTA4H P09960 2/20 0.41
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
TSHR P16473 2/20 0.36
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841043 0.84 LTA4H (0.50) APPMAPTALDH1A1LTA4HCA1
SCHEMBL2883028 0.84 LTA4H (0.50) APPMAPTALDH1A1LTA4HCA1
SCHEMBL3845620 0.84 LTA4H (0.50) APPMAPTALDH1A1LTA4HCA1
SCHEMBL28553350 0.84 APP (0.40) APPCA1CA2TSHRCYP3A4
SCHEMBL1986810 0.84 APP (0.40) APPCA1CA2TSHRCYP3A4
SCHEMBL3671300 0.83 APP (0.40) APPNPC1MAPTRAB9AALDH1A1
SCHEMBL9987935 0.81 TRPV1 (0.46) APPRAB9AALDH1A1LTA4HCA1
SCHEMBL13692793 0.79 NPC1 (0.44) APPNPC1MAPTRAB9AALDH1A1
SCHEMBL10706950 0.78 ESR1 (0.45) APPNPC1MAPTRAB9AALDH1A1
SCHEMBL3679342 0.78 APP (0.37) APPNPC1MAPTRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090221779-A1 FILM FORMING COMPOSITION, INSULATING FILM, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed
US-20090221779-A1 FILM FORMING COMPOSITION, INSULATING FILM, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221779-A1 FILM FORMING COMPOSITION, INSULATING FILM, AND ELECTRONIC DEVICE CCNT1, CCNA1, BMI1 APP 1761/4885NPC1 2449/4885MAPT 2394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.