Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 18/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343002 | 0.90 | CCR9 (0.81) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL12221307 | 0.90 | CCR9 (0.84) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL343218 | 0.90 | CCR9 (0.77) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL13693107 | 0.90 | CCR9 (0.77) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL2167634 | 0.88 | CCR9 (1.00) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL343741 | 0.87 | CCR9 (0.73) | CCR9 | |
| SCHEMBL344016 | 0.86 | CCR9 (1.00) | CCR9LMNAHTT | |
| SCHEMBL344455 | 0.85 | CCR9 (0.76) | CCR9LMNAHTT | |
| SCHEMBL343457 | 0.84 | CCR9 (1.00) | CCR9 | |
| SCHEMBL343875 | 0.83 | CCR9 (1.00) | CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582661-B2 | Aryl sulfonamides | CHEMOCENTRYX, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-7582661-B2 | Aryl sulfonamides | CHEMOCENTRYX, INC. (US) | 2009-09-01 | — | — | US | disclosed |