Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 19/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343606 | 0.91 | CCR9 (0.83) | CCR9LMNATP53MAPTHTT | |
| SCHEMBL342212 | 0.86 | CCR9 (0.78) | CCR9LMNAHTT | |
| SCHEMBL344126 | 0.85 | CCR9 (0.78) | CCR9LMNATP53MAPTHTT | |
| SCHEMBL28301 | 0.85 | CCR9 (0.74) | CCR9LMNATP53MAPTHTT | |
| SCHEMBL12474689 | 0.84 | LMNA (0.72) | CCR9LMNATP53MAPTHTT | |
| SCHEMBL344267 | 0.83 | CCR9 (0.80) | CCR9LMNATP53MAPTHTT | |
| SCHEMBL13016871 | 0.83 | CCR9 (0.71) | CCR9LMNATP53MAPTHTT | |
| SCHEMBL343792 | 0.83 | CCR9 (0.73) | CCR9LMNATP53MAPTHTT | |
| SCHEMBL11934697 | 0.82 | CCR9 (0.70) | CCR9LMNATP53MAPTHTT | |
| SCHEMBL12359420 | 0.81 | CCR9 (0.68) | CCR9LMNATP53MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582661-B2 | Aryl sulfonamides | CHEMOCENTRYX, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-7582661-B2 | Aryl sulfonamides | CHEMOCENTRYX, INC. (US) | 2009-09-01 | — | — | US | disclosed |