Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.32 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.32 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23064092 | 0.82 | CES2 (0.52) | TDP1USP2SPHK1TSHRHTT | |
| SCHEMBL23064093 | 0.82 | CES2 (0.52) | TDP1USP2SPHK1TSHRHTT | |
| SCHEMBL24034224 | 0.81 | TDP1 (0.38) | TDP1 | |
| SCHEMBL18784692 | 0.81 | TDP1 (0.36) | TDP1TSHR | |
| SCHEMBL32660731 | 0.79 | TDP1 (0.39) | TDP1 | |
| SCHEMBL1172462 | 0.79 | TDP1 (0.46) | TDP1USP2SPHK1TSHRHTT | |
| SCHEMBL29488235 | 0.79 | TDP1 (0.42) | TDP1 | |
| SCHEMBL80455 | 0.78 | TDP1 (0.52) | TDP1USP2SPHK1TSHRHTT | |
| SCHEMBL23064087 | 0.77 | CES2 (0.59) | TDP1USP2SPHK1HTTCES2 | |
| SCHEMBL23064088 | 0.77 | CES2 (0.59) | TDP1USP2SPHK1HTTCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009112418-A1 | NOVEL POLYCARBONATE POLYORGANOSILOXANE AND/OR POLYURETHANE POLYORGANOSILOXANE COMPOUNDS | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2009-09-17 | — | — | WO | disclosed |