Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1038726 | 0.90 | GLO1 (0.61) | SYK | |
| SCHEMBL13695297 | 0.89 | SYK (0.53) | SYK | |
| SCHEMBL13695322 | 0.89 | SYK (0.64) | SYK | |
| SCHEMBL13695177 | 0.87 | SYK (0.61) | SYK | |
| SCHEMBL12765459 | 0.79 | ALK (0.67) | SYK | |
| SCHEMBL12765437 | 0.79 | GLO1 (0.68) | SYK | |
| Hydrochloric Acid SCHEMBL1037398 | 0.78 | GLO1 (0.67) | SYK | |
| SCHEMBL27631566 | 0.78 | SYK (0.81) | SYK | |
| SCHEMBL1035671 | 0.78 | GLO1 (0.61) | SYK | |
| SCHEMBL12765469 | 0.77 | GLO1 (0.60) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009112490-A1 | SULFONAMIDES AS ZAP-70 INHIBITORS | CELLZOME LIMITED (GB) | 2009-09-17 | — | — | WO | disclosed |