⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912319 | 1.00 | — | — | |
| SCHEMBL9912340 | 0.81 | HIF1A (0.32) | — | |
| SCHEMBL9912322 | 0.81 | HIF1A (0.32) | — | |
| SCHEMBL13696397 | 0.81 | HIF1A (0.32) | — | |
| SCHEMBL9912342 | 0.81 | HIF1A (0.32) | — | |
| SCHEMBL13392126 | 0.77 | — | — | |
| SCHEMBL12000784 | 0.74 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL11924464 | 0.73 | — | — | |
| SCHEMBL13696402 | 0.73 | — | — | |
| SCHEMBL9912326 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227524-A1 | ANTIVIRAL THERAPEUTIC AGENTS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2009-09-10 | — | — | US | disclosed |