Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154611 | 0.89 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL4155131 | 0.87 | PTGER1 (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL4914240 | 0.85 | PTGER1 (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL5696865 | 0.85 | PTGER1 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL4159378 | 0.83 | CYP1A2 (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL5620804 | 0.83 | CYP2C9 (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL4156061 | 0.83 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL4919224 | 0.81 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL4158080 | 0.81 | PTGER1 (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL4147291 | 0.79 | PTGER1 (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | C1R, CYP1B1, ADORA2B | CYP1A2 72/4885CYP3A4 271/4885CYP2C9 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.