Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4005947 | 0.83 | TSHR (0.47) | SMN1; SMN2KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL4005943 | 0.83 | TSHR (0.47) | SMN1; SMN2KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL14899157 | 0.77 | TSHR (0.41) | SMN1; SMN2KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL4013088 | 0.76 | TSHR (0.54) | SMN1; SMN2KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL2048794 | 0.76 | TSHR (0.54) | SMN1; SMN2KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL7807838 | 0.76 | TSHR (0.54) | SMN1; SMN2KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL9738473 | 0.74 | TSHR (0.52) | SMN1; SMN2KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL9738478 | 0.74 | TSHR (0.52) | SMN1; SMN2KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL13116685 | 0.74 | TSHR (0.52) | SMN1; SMN2KDM4EL3MBTL1TDP1KMT2A | |
| SCHEMBL27856036 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4EL3MBTL1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240067-A1 | METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240067-A1 | METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND | SQOR, NQO1, PBRM1 | SMN1; SMN2 4471/4885KDM4E 3362/4885L3MBTL1 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.