Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 18/20 | 0.85 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | HPD | P32754 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4155528 | 0.94 | PTGER1 (0.93) | PTGER1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL4150412 | 0.93 | PTGER1 (0.92) | PTGER1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL4170893 | 0.93 | PTGER1 (0.82) | PTGER1CYP2C9CYP3A4CYP2C19HPD | |
| SCHEMBL4158076 | 0.92 | PTGER1 (0.73) | PTGER1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL5620085 | 0.92 | PTGER1 (1.00) | PTGER1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL13697118 | 0.91 | PTGER1 (0.74) | PTGER1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL4154652 | 0.90 | PTGER1 (0.86) | PTGER1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL4149262 | 0.90 | PTGER1 (0.82) | PTGER1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL4154402 | 0.89 | PTGER1 (0.69) | PTGER1CYP2C9CYP3A4CYP2C19HPD | |
| SCHEMBL4150581 | 0.89 | PTGER1 (0.73) | PTGER1CYP2C9CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | C1R, CYP1B1, ADORA2B | PTGER1 246/4885CYP2C9 5/4885CYP3A4 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.