Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.47 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4155709 | 0.88 | KMT2A (0.54) | ABCG2KMT2AMAPTSMN1; SMN2DYRK1A | |
| SCHEMBL13697360 | 0.88 | ABCG2 (0.55) | ABCG2KMT2AMAPTSMN1; SMN2DYRK1A | |
| SCHEMBL4164355 | 0.78 | SMN1; SMN2 (0.53) | ABCG2KMT2AMAPTSMN1; SMN2DYRK1A | |
| SCHEMBL6599966 | 0.77 | ABCG2 (0.53) | ABCG2KMT2AMAPTSMN1; SMN2DYRK1A | |
| SCHEMBL17154359 | 0.77 | KMT2A (0.54) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL4163828 | 0.76 | KMT2A (0.59) | ABCG2KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL17154385 | 0.75 | KMT2A (0.60) | KMT2AMAPTSMN1; SMN2DYRK1AMEN1 | |
| SCHEMBL23458119 | 0.74 | KMT2A (0.51) | ABCG2KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL642700 | 0.73 | KMT2A (0.81) | KMT2AMAPTSMN1; SMN2MEN1GAA | |
| SCHEMBL16922176 | 0.73 | KMT2A (0.81) | KMT2AMAPTSMN1; SMN2MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9127164-B2 | Fluorescent dyes and uses thereof | ALMAC SCIENCES (SCOTLAND) LIMITED (GB) | 2015-09-08 | — | — | US | disclosed |
| US-20090226940-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI SCOTLAND LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
| WO-2007049057-A2 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI SCOTLAND LIMITED (GB) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226940-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ACR, ANXA5, GLB1 | ABCG2 177/4885KMT2A 4502/4885MAPT 2114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.