Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17075238 | 0.82 | RAD51 (0.44) | KDM4EALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL14815466 | 0.82 | RAD51 (0.44) | KDM4EALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL12145464 | 0.82 | IDO1 (0.45) | KDM4EALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL17075173 | 0.82 | IDO1 (0.41) | KDM4EALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL29484665 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL12145438 | 0.80 | IKBKB (0.51) | KDM4EALDH1A1TP53SMN1; SMN2NPC1 | |
| SCHEMBL12145440 | 0.80 | MAPT (0.47) | KDM4EALDH1A1TP53SMN1; SMN2PARP1 | |
| SCHEMBL14127581 | 0.80 | PRKDC (0.42) | ALDH1A1TP53SMN1; SMN2PARP1MAPT | |
| SCHEMBL12145459 | 0.80 | PRKDC (0.42) | KDM4EALDH1A1TP53SMN1; SMN2PARP1 | |
| SCHEMBL14232581 | 0.80 | PRKDC (0.42) | KDM4EALDH1A1TP53SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930614-A | Benzo [4,5] imidazo [2,1-a ] isoquinoline compound and preparation method and application thereof | 烟台大学 | 2025-05-06 | — | — | CN | claimed |
| CN-118930483-A | Synthesis method of isoquinolone selenocyanate | 新疆大学 | 2024-11-12 | — | — | CN | claimed |
| CN-116789664-A | Method for synthesizing benzoimidazole isoquinoline analogue containing trifluoromethyl | 长沙理工大学 | 2023-09-22 | — | — | CN | claimed |
| CN-113698399-B | Isoquinoline compound and preparation method and application thereof | 浙江省人民医院 | 2022-05-27 | — | — | CN | claimed |
| EP-2872506-A1 | METHOD FOR PREPARING SUBSTITUTED TRIAZOLOPYRIDINES | Bayer Pharma Aktiengesellschaft (DE) | 2015-05-20 | — | — | EP | claimed |
| WO-2014009219-A1 | METHOD FOR PREPARING SUBSTITUTED TRIAZOLOPYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-01-16 | — | — | WO | claimed |
| CN-122059959-A | Synthesis method and application of pyrrolo [2,1-a ] isoquinoline compound | 河南工业大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-119930614-B | Benzo [4,5] imidazo [2,1-a ] isoquinoline compound and preparation method and application thereof | 烟台大学 | 2025-12-16 | — | — | CN | disclosed |
| CN-119930614-B | Benzo [4,5] imidazo [2,1-a ] isoquinoline compound and preparation method and application thereof | 烟台大学 | 2025-12-16 | — | — | CN | disclosed |
| CN-119930614-A | Benzo [4,5] imidazo [2,1-a ] isoquinoline compound and preparation method and application thereof | 烟台大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-119930614-A | Benzo [4,5] imidazo [2,1-a ] isoquinoline compound and preparation method and application thereof | 烟台大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-119930614-A | Benzo [4,5] imidazo [2,1-a ] isoquinoline compound and preparation method and application thereof | 烟台大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-118930483-A | Synthesis method of isoquinolone selenocyanate | 新疆大学 | 2024-11-12 | — | — | CN | disclosed |
| WO-2014008982-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-01-16 | — | — | WO | disclosed |
| WO-2012163465-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012163465-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2012-12-06 | — | — | WO | disclosed |
| US-20110284799-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110284799-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| US-20110284799-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010086089-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110284799-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | KDM4E 3816/4885ALDH1A1 3721/4885LMNA 4436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.