Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 3/20 | 0.35 |
| ▸ | GABRD | O14764 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.35 |
| ▸ | GABRE | P78334 | 3/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13697475 | 0.90 | PTGER1 (0.44) | SCN9ACYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL13696906 | 0.88 | MAOB (0.44) | CYP1A2SCN9ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13696718 | 0.88 | PTGER1 (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL4158553 | 0.87 | PTGER1 (0.39) | CYP1A2SCN9ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4153864 | 0.87 | PTGER1 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL13696729 | 0.87 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL4164138 | 0.86 | PTGER1 (0.43) | CYP1A2SCN9ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4159375 | 0.86 | PTGER1 (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL4162625 | 0.86 | PTGER1 (0.43) | CYP1A2SCN9ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4160639 | 0.85 | PTGER1 (0.46) | CYP1A2SCN9ACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | C1R, CYP1B1, ADORA2B | CYP1A2 72/4885SCN9A 1429/4885CYP3A4 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.