Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 4/20 | 0.56 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.55 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.53 |
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | NPY4R | P50391 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13697492 | 0.88 | CALCRL (0.56) | — | |
| SCHEMBL31516395 | 0.88 | CXCR4 (0.57) | CXCR4NTSR2NTSR1SORT1DPP3 | |
| SCHEMBL30435876 | 0.86 | NPY1R (0.66) | CXCR4NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL30608427 | 0.85 | NTSR2 (0.57) | NTSR2NTSR1SORT1C5AR1DPP3 | |
| SCHEMBL31499421 | 0.85 | DPP3 (0.60) | NTSR2NTSR1SORT1DPP3CXCL8 | |
| SCHEMBL30495674 | 0.85 | NPY1R (0.60) | CXCR4CXCL8NPY1RNPY2RNPY4R | |
| SCHEMBL30386453 | 0.85 | CXCL8 (0.56) | C5AR1DPP3CXCL8 | |
| SCHEMBL31422677 | 0.84 | CXCL8 (0.55) | CXCR4CXCL8CAPN1CTSB | |
| SCHEMBL29756048 | 0.84 | C5AR1 (0.63) | CXCR4NTSR2NTSR1SORT1C5AR1 | |
| SCHEMBL30893565 | 0.84 | CXCR4 (0.63) | CXCR4NTSR2NTSR1SORT1CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150899-B2 | Identification of compounds modifying a cellular response | 2CUREX (DK) | 2015-10-06 | — | — | US | disclosed |
| US-9150899-B2 | Identification of compounds modifying a cellular response | 2CUREX (DK) | 2015-10-06 | — | — | US | disclosed |
| US-20130123140-A1 | IDENTIFICATION OF COMPOUNDS MODIFYING A CELLULAR RESPONSE | 2CUREX (DK) | 2013-05-16 | — | — | US | disclosed |
| US-20130123140-A1 | IDENTIFICATION OF COMPOUNDS MODIFYING A CELLULAR RESPONSE | 2CUREX (DK) | 2013-05-16 | — | — | US | disclosed |
| US-20090239755-A1 | Identification of Compounds Modifying A Cellular Response | 2CUREX (DK) | 2009-09-24 | — | — | US | disclosed |
| US-20090239755-A1 | Identification of Compounds Modifying A Cellular Response | 2CUREX (DK) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239755-A1 | Identification of Compounds Modifying A Cellular Response | MCL1, PMAIP1, CDC37 | CXCR4 3406/4885NTSR2 4338/4885NTSR1 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.