Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 6/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10048288 | 0.90 | NR1H2 (0.38) | NR1H2NR1H3NFKB1NFKB2RELA | |
| SCHEMBL13895090 | 0.90 | NR1H2 (0.38) | NR1H2NR1H3NFKB1NFKB2RELA | |
| SCHEMBL13698048 | 0.88 | NFKB1 (0.40) | NFKB1NFKB2RELAKDM1AACHE | |
| SCHEMBL15996705 | 0.88 | NFKB1 (0.40) | NFKB1NFKB2RELAKDM1AACHE | |
| SCHEMBL13698112 | 0.85 | NFKB1 (0.55) | NR1H2NR1H3NFKB1NFKB2RELA | |
| SCHEMBL13698111 | 0.85 | NFKB1 (0.55) | NR1H2NR1H3NFKB1NFKB2RELA | |
| SCHEMBL10048264 | 0.85 | NFKB1 (0.55) | NR1H2NR1H3NFKB1NFKB2RELA | |
| SCHEMBL13895145 | 0.75 | NFKB1 (0.54) | NR1H2NR1H3NFKB1NFKB2RELA | |
| SCHEMBL13895010 | 0.75 | NFKB1 (0.54) | NR1H2NR1H3NFKB1NFKB2RELA | |
| SCHEMBL10048501 | 0.75 | NR1H2 (0.49) | NR1H2NR1H3NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227527-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING BONE DISEASE, FUNCTIONAL FOOD OR HEALTH FOOD AND PHARMACEUTICAL PREPARATION COMPRISING THEREOF AS ACTIVE INGREDIENT | Akihisa, Toshihiro (JP) | 2009-09-10 | — | — | US | disclosed |
| EP-2050442-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND/OR TREATMENT OF BONE DISEASE, FUNCTIONAL FOOD OR HEALTH FOOD COMPRISING THE COMPOSITION, AND PHARMACEUTICAL PREPARATION COMPRISING THE COMPOSITION AS ACTIVE INGREDIENT | Akihisa, Toshihiro (JP) | 2009-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227527-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND/OR TREATING BONE DISEASE, FUNCTIONAL FOOD OR HEALTH FOOD AND PHARMACEUTICAL PREPARATION COMPRISING THEREOF AS ACTIVE INGREDIENT | HRH1, HRH2, HRH3 | NR1H2 80/4885NR1H3 155/4885NFKB1 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.