⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788556 | 1.00 | — | — | |
| SCHEMBL14080945 | 1.00 | — | — | |
| SCHEMBL10211464 | 1.00 | — | — | |
| SCHEMBL18642668 | 1.00 | — | — | |
| Ethane SCHEMBL15059275 | 0.97 | LMNA (0.32) | — | |
| Methyl Alcohol SCHEMBL22770521 | 0.76 | — | — | |
| SCHEMBL31673150 | 0.76 | — | — | |
| SCHEMBL14476389 | 0.76 | — | — | |
| SCHEMBL11917825 | 0.76 | — | — | |
| SCHEMBL26279 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595253-B2 | Benzamides of pyrazolylamino-pyrimidinyl derivatives, and compositions and methods thereof | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2026-04-07 | — | — | US | disclosed |
| US-20250381202-A1 | PRODRUG KIT FOR MULTI-PRONGED CHEMOTHERAPY | ZOUNEK ALEX (DE) | 2025-12-18 | — | — | US | disclosed |
| US-12421213-B2 | Benzamides of pyrazolylamino- pyrimidinyl derivatives, and compositions and methods thereof | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2025-09-23 | — | — | US | disclosed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |
| US-20250115586-A1 | BENZAMIDES OF PYRAZOLYLAMINO- PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO LTD (CN) | 2025-04-10 | — | — | US | disclosed |
| CN-119118999-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118955477-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118903141-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-118903142-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-11-08 | — | — | CN | disclosed |
| WO-2024218296-A1 | COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF LEUCINE-RICH REPEAT KINASE 2 (LRRK2) INHIBITORS | H. LUNDBECK A/S (DK) | 2024-10-24 | — | — | WO | disclosed |
| US-6258574-B1 | STEREOSPECIFICALLY ESTERIFYING A RACEMIC MIXTURE OF CIS-SUBSTITUTED TETRAHYDROPYRAN-4-OL USING ESTERASE | ZENECA LIMITED (GB) | 2001-07-10 | — | — | US | disclosed |
| US-5962282-A | PRODUCING CIS 2-SUBSTITUTED TETRAHYDROPYRAN-4-OL BY STEREOSPECIFICALLY HYDROLYSING AN ESTER DERIVATIVE USING HYDROLASE IN A RACEMIC MIXTURE; FOR FORMING OPTICALLY ACTIVE KETONE DERIVATIVES | AVECIA LIMITED (GB) | 1999-10-05 | — | — | US | disclosed |
| EP-0862646-A1 | PRODUCTION OF OPTICALLY ACTIVE 2-SUBSTITUTED TETRAHYDROPYRAN-4-ONES | ZENECA LIMITED (GB) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997019185-A1 | PRODUCTION OF OPTICALLY ACTIVE 2-SUBSTITUTED TETRAHYDROPYRAN-4-ONES | ZENECA LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |
| CN-1128029-A | Thiazole derivatives as lipoxygenase inhibitors | ZENECA LTD (GB) | 1996-07-31 | — | — | CN | disclosed |
| CN-1121715-A | 4-aryl-4-hydroxy-tetrahydropyrans and 3-aryl-3-hydroxy-tetrahydrofurans as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0591795-B1 | Process for hydrogenolysis of citric acid | BASF AG (DE) | 1996-01-31 | — | — | EP | disclosed |
| US-5478843-A | Administering as inhibitors of the enzyme 5-lipoxygenase | ZENECA LIMITED (GB) | 1995-12-26 | — | — | US | disclosed |
| WO-1995004055-A1 | THIAZOLE DERIVATIVES AS LIPOXYGENASE INHIBITORS | ZENECA LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |
| EP-0636624-A1 | Thiazole derivatives as lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1995-02-01 | — | — | EP | disclosed |