SCHEMBL13698654

SCHEMBL13698654

O=C(NC[C@@H]1CN(c2ccc(S(=O)(=O)Cl)cc2)C(=O)O1)c1ccc(Cl)s1

nearest known ligand 0.78

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.78
F2 P00734 2/20 0.69
ABCB11 O95342 1/20 0.69
ST14 Q9Y5Y6 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL87148 1.00 F10 (0.78) F10F2ABCB11ST14
SCHEMBL77177 0.89 F10 (0.78) F10F2ABCB11ST14
SCHEMBL77072 0.88 F10 (1.00) F10F2ABCB11ST14
SCHEMBL78473 0.88 F10 (0.96) F10F2ABCB11ST14
SCHEMBL77773 0.88 F10 (0.82) F10F2ABCB11ST14
SCHEMBL78408 0.88 F10 (0.82) F10F2ABCB11ST14
SCHEMBL76768 0.87 F10 (0.98) F10F2ABCB11ST14
SCHEMBL15247387 0.87 F10 (0.80) F10F2ABCB11ST14
SCHEMBL24177659 0.86 F10 (1.00) F10F2ABCB11ST14
SCHEMBL13698655 0.86 F10 (1.00) F10F2ABCB11ST14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7592339-B2 Substituted oxazolidinones and their use in the field of blood coagulation BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2009-09-22 US disclosed
US-7592339-B2 Substituted oxazolidinones and their use in the field of blood coagulation BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2009-09-22 US disclosed