SCHEMBL24177659

SCHEMBL24177659

O=C(NC[C@H]1CN(c2ccccc2)C(=O)O1)c1ccc(Cl)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 1.00
F2 P00734 4/20 0.75
ABCB11 O95342 1/20 0.72
ST14 Q9Y5Y6 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13698655 1.00 F10 (1.00) F10F2ABCB11ST14
SCHEMBL77589 1.00 F10 (1.00) F10F2ABCB11ST14
SCHEMBL78408 0.90 F10 (0.82) F10F2ABCB11ST14
SCHEMBL77773 0.90 F10 (0.82) F10F2ABCB11ST14
SCHEMBL87034 0.89 F10 (1.00) F10F2ABCB11ST14
SCHEMBL15247387 0.89 F10 (0.80) F10F2ABCB11ST14
SCHEMBL16234736 0.89 F10 (0.80) F10
SCHEMBL27853869 0.89 F10 (0.80) F10
SCHEMBL27853870 0.89 F10 (0.80) F10
SCHEMBL77041 0.89 F10 (0.84) F10F2ABCB11ST14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227425-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2023-07-20 US disclosed
US-20230227425-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2023-07-20 US disclosed
US-20220002263-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2022-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227425-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION CFH, DOHH, CTSH F10 560/4885F2 915/4885ABCB11 4802/4885
US-20220002263-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION CFH, DOHH, CTSH F10 560/4885F2 915/4885ABCB11 4802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.