Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 4/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2206878 | 0.81 | NOTUM (1.00) | NOTUMHSD17B10TRIM24CYP11B1CYP11B2 | |
| SCHEMBL2203840 | 0.79 | NOTUM (0.83) | NOTUMHSD17B10TRIM24POLBKMT2A | |
| SCHEMBL13699025 | 0.78 | NOTUM (0.60) | NOTUMHSD17B3POLBKMT2AMEN1 | |
| SCHEMBL6985785 | 0.75 | KMT2A (0.60) | NOTUMPOLBKMT2AMEN1MAPT | |
| Trifluoroacetic Acid SCHEMBL31438768 | 0.74 | NOTUM (0.82) | NOTUMHSD17B10TRIM24CYP11B1CYP11B2 | |
| SCHEMBL13699015 | 0.73 | NOTUM (0.57) | NOTUMHSD17B10TRIM24HSD17B3POLB | |
| SCHEMBL2208006 | 0.73 | NOTUM (0.78) | NOTUMHSD17B10TRIM24CYP11B1CYP11B2 | |
| SCHEMBL21172770 | 0.71 | NOTUM (0.62) | NOTUMHSD17B10TRIM24CYP11B1CYP11B2 | |
| SCHEMBL23090380 | 0.69 | NOTUM (0.63) | NOTUMHSD17B10POLBLMNAMAPT | |
| SCHEMBL5567815 | 0.69 | NOTUM (0.76) | NOTUMHSD17B10TRIM24CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | NOTUM 2609/4885HSD17B10 3929/4885TRIM24 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.