Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699025 | 0.89 | NOTUM (0.60) | KMT2AMEN1NOTUMTDP1TP53 | |
| SCHEMBL30804501 | 0.89 | THRB (0.58) | KMT2AMEN1NOTUMTDP1TP53 | |
| SCHEMBL31452930 | 0.83 | THRB (0.53) | KMT2AMEN1TDP1TP53THRB | |
| SCHEMBL10274847 | 0.81 | NOTUM (0.65) | KMT2AMEN1NOTUMTP53THRB | |
| SCHEMBL5533649 | 0.81 | NOTUM (0.65) | KMT2AMEN1NOTUMTDP1POLB | |
| SCHEMBL13699015 | 0.81 | NOTUM (0.57) | KMT2AMEN1NOTUMTDP1TP53 | |
| SCHEMBL594255 | 0.79 | NOTUM (0.63) | KMT2AMEN1NOTUMTDP1POLB | |
| SCHEMBL395823 | 0.79 | NOTUM (0.63) | KMT2AMEN1NOTUMTDP1POLB | |
| SCHEMBL4898938 | 0.79 | THRB (0.54) | KMT2AMEN1TDP1TP53THRB | |
| SCHEMBL23675063 | 0.79 | NPC1 (0.49) | KMT2ATP53THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-6620809-B2 | Useful in treating or in preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-09-16 | — | — | US | disclosed |
| EP-1106608-B1 | Substituted (dihydro)benzoxazine and (dihydro)benzothiazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-05 | — | — | EP | disclosed |
| US-20010003747-A1 | New substituted (dihydro)benzoxazine and (dihydro)benzothiazine compounds | LES LABORATOIRES SERVIER (FR) | 2001-06-14 | — | — | US | disclosed |
| EP-1106608-A1 | Substituted (dihydro)benzoxazine and (dihydro)benzothiazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003747-A1 | New substituted (dihydro)benzoxazine and (dihydro)benzothiazine compounds | MTNR1A, MTNR1B, SQOR | KMT2A 800/4885MEN1 1534/4885NOTUM 4336/4885 |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | NTRK1, NGF, SMN1; SMN2 | KMT2A 4578/4885MEN1 643/4885NOTUM 2998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.