⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10834459 | 0.71 | — | — | |
| SCHEMBL198094 | 0.71 | — | — | |
| SCHEMBL31243289 | 0.71 | — | — | |
| SCHEMBL879185 | 0.67 | — | — | |
| SCHEMBL1145625 | 0.67 | — | — | |
| SCHEMBL1695759 | 0.67 | — | — | |
| SCHEMBL2141400 | 0.67 | — | — | |
| SCHEMBL13429908 | 0.67 | — | — | |
| SCHEMBL9479395 | 0.67 | — | — | |
| SCHEMBL1657188 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221584-A1 | Bisaryl-sulfonamides | AMGEN INC. | 2009-09-03 | — | — | US | disclosed |
| US-7544702-B2 | Bisaryl-sulfonamides | AMGEN INC. (US) | 2009-06-09 | — | — | US | disclosed |