⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30361232 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1283668 | 0.97 | NOS3 (0.48) | — | |
| SCHEMBL10834459 | 0.77 | — | — | |
| SCHEMBL20376676 | 0.72 | — | — | |
| SCHEMBL29353771 | 0.71 | — | — | |
| SCHEMBL34048 | 0.71 | — | — | |
| SCHEMBL1257460 | 0.71 | PIK3CD (0.73) | — | |
| SCHEMBL29740321 | 0.71 | PIK3CD (0.73) | — | |
| Hydrochloric Acid SCHEMBL7654260 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL913230 | 0.69 | NOS3 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912901-A | Water-triggered adhesive and preparation method and application thereof | 北京林业大学 | 2025-05-02 | — | — | CN | claimed |
| CN-119912901-A | Water-triggered adhesive and preparation method and application thereof | 北京林业大学 | 2025-05-02 | — | — | CN | disclosed |
| CN-115974414-B | Low-expansion corrosion-resistant high borosilicate glass reagent bottle and preparation method thereof | 江苏华鸥玻璃有限公司 | 2024-09-13 | — | — | CN | disclosed |
| WO-2021050964-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2021-03-18 | — | — | WO | disclosed |
| US-10640476-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | XW LABORATORIES INC. (KY) | 2020-05-05 | — | — | US | disclosed |
| EP-1954277-B1 | AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS | VERTEX PHARMA (US) | 2017-01-18 | — | — | EP | disclosed |
| WO-2015175707-A1 | HSP70 MODULATORS AND METHODS FOR MAKING AND USING THE SAME | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2015-11-19 | — | — | WO | disclosed |
| EP-2021340-B1 | BETA-AMYLOID PET IMAGING AGENTS | US GOVERNMENT (US) | 2014-07-23 | — | — | EP | disclosed |
| US-8637511-B2 | Aminopyrimidines useful as kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130303516-A1 | NOVEL TRIAZINE COMPOUNDS | SPHAERA PHARMA PTE. LTD. (SG) | 2013-11-14 | — | — | US | disclosed |
| US-7767672-B2 | Aminopyrimidines useful as kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-08-03 | — | — | US | disclosed |
| US-20090221584-A1 | Bisaryl-sulfonamides | AMGEN INC. | 2009-09-03 | — | — | US | disclosed |
| US-7544702-B2 | Bisaryl-sulfonamides | AMGEN INC. (US) | 2009-06-09 | — | — | US | disclosed |
| EP-1954277-A2 | AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS | Vertex Pharmceuticals Incorporated (US) | 2008-08-13 | — | — | EP | disclosed |
| US-20070259869-A1 | Aminopyrimidines useful as kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-11-08 | — | — | US | disclosed |
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007056221-A2 | AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056221-A2 | AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-05-18 | — | — | WO | disclosed |
| US-4146642-A | ANTHELMINTICS | MERCK & CO., INC. (US) | 1979-03-27 | — | — | US | disclosed |
| US-4105767-A | ANTHELMINTICS | MERCK & CO., INC. (US) | 1978-08-08 | — | — | US | disclosed |