Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | RHOC | P08134 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31144903 | 0.91 | NOTUM (0.56) | NOTUMMAPTRAB9ARHOCRHOA | |
| SCHEMBL31144913 | 0.87 | NOTUM (0.58) | NOTUMMAPTRAB9ARHOCRHOA | |
| SCHEMBL17703910 | 0.85 | NOTUM (0.59) | NOTUMMAPTRAB9ACES2LMNA | |
| SCHEMBL13699188 | 0.83 | PLA2G2A (0.53) | CES2RHOCRHOAKMT2AMRGPRX4 | |
| SCHEMBL1999038 | 0.82 | NOTUM (0.77) | NOTUMMAPTCES2LMNAKDM4E | |
| SCHEMBL25170108 | 0.81 | NOTUM (0.55) | NOTUMCES2LMNASCN9AMRGPRX4 | |
| SCHEMBL1189091 | 0.81 | NOTUM (0.66) | NOTUMCES2LMNAKDM4ECFTR | |
| SCHEMBL2809253 | 0.80 | MAPT (0.59) | MAPTRAB9ALMNAKDM4ETDP1 | |
| SCHEMBL31179766 | 0.80 | NOTUM (0.64) | NOTUMMAPTCES2LMNAKDM4E | |
| SCHEMBL2809599 | 0.79 | ATF1 (0.46) | NOTUMHTTKDM4EKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009113704-A2 | FLUORINE-CONTAINING COMPOUND AND METHOD FOR DETECTING BIOMOLECULE USING THE SAME | KYOTO UNIVERSITY (JP) | 2009-09-17 | — | — | WO | disclosed |