Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699277 | 0.90 | PKM (0.45) | TAS1R3TAS1R1FGFR1MCHR1PDE4D | |
| SCHEMBL13699326 | 0.90 | PKM (0.42) | TAS1R3TAS1R1MCHR1PKMSMN1; SMN2 | |
| SCHEMBL13699206 | 0.87 | PKM (0.45) | TAS1R3TAS1R1MCHR1PDE4DCYP2D6 | |
| SCHEMBL4242226 | 0.87 | SMN1; SMN2 (0.43) | TAS1R3TAS1R1FGFR1MCHR1PDE4D | |
| SCHEMBL13699270 | 0.87 | PKM (0.44) | TAS1R3TAS1R1PKMMAPTNPC1 | |
| SCHEMBL13699133 | 0.86 | PKM (0.45) | TAS1R3TAS1R1MCHR1PDE4DCYP2D6 | |
| SCHEMBL13699147 | 0.86 | PKM (0.41) | TAS1R3TAS1R1PKMCYP3A4 | |
| SCHEMBL13699154 | 0.85 | PKM (0.42) | TAS1R3TAS1R1MCHR1CYP2D6PKM | |
| SCHEMBL13699114 | 0.85 | CYP2D6 (0.45) | TAS1R3TAS1R1PDE4DCYP2D6SMN1; SMN2 | |
| SCHEMBL4229209 | 0.84 | PKM (0.43) | TAS1R3TAS1R1FGFR1MCHR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | TAS1R3 1436/4885TAS1R1 1073/4885FGFR1 581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.