Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699301 | 0.84 | P2RX7 (0.72) | P2RX7TRPA1SIGMAR1 | |
| SCHEMBL1199855 | 0.83 | P2RX7 (0.69) | P2RX7TRPA1SIGMAR1 | |
| SCHEMBL12878440 | 0.83 | P2RX7 (0.69) | P2RX7TRPA1SIGMAR1 | |
| SCHEMBL5808815 | 0.81 | P2RX7 (0.82) | P2RX7TRPA1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL1199833 | 0.81 | P2RX7 (0.62) | P2RX7TRPA1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL5816280 | 0.79 | P2RX7 (1.00) | P2RX7TRPA1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL6356869 | 0.78 | P2RX7 (0.78) | P2RX7TRPA1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL5815398 | 0.78 | P2RX7 (1.00) | P2RX7TRPA1SIGMAR1 | |
| SCHEMBL29409600 | 0.78 | P2RX7 (1.00) | P2RX7TRPA1SIGMAR1 | |
| SCHEMBL29384490 | 0.78 | P2RX7 (1.00) | P2RX7TRPA1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247316-B1 | IMAGING THE CENTRAL NERVOUS SYSTEM | GE HEALTHCARE LTD (GB) | 2013-11-06 | — | — | EP | disclosed |
| WO-2009106564-A2 | IMAGING THE CENTRAL NERVOUS SYSTEM | GE HEALTHCARE LIMITED (GB) | 2009-09-03 | — | — | WO | disclosed |