Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700403 | 0.89 | TP53 (0.40) | MAPTTHRBTP53ALDH1A1CYP2C9 | |
| SCHEMBL13700414 | 0.81 | MAPT (0.38) | MAPTTHRBMAPK14TP53ALDH1A1 | |
| SCHEMBL13700404 | 0.80 | MAPT (0.39) | MAPTTHRBTP53ALDH1A1HPGD | |
| SCHEMBL13700703 | 0.75 | MAPT (0.37) | MAPTTHRBTP53ALDH1A1CYP2C9 | |
| SCHEMBL13699412 | 0.75 | MAPT (0.37) | MAPTTHRBTP53ALDH1A1HPGD | |
| SCHEMBL13700442 | 0.74 | HSP90AA1 (0.37) | MAPTTP53ALDH1A1CYP2C9HPGD | |
| SCHEMBL13700464 | 0.74 | GAA (0.37) | MAPTTP53ALDH1A1HPGDKDM4E | |
| SCHEMBL13700394 | 0.74 | CA12 (0.50) | MAPTALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL13699458 | 0.73 | KDM4E (0.37) | MAPTTHRBTP53ALDH1A1HPGD | |
| SCHEMBL13700393 | 0.72 | CA12 (0.44) | MAPTTP53ALDH1A1CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2103445-A1 | Heat resistance improver and reversible thermosensitive recording medium | Ricoh Company, Ltd. (JP) | 2009-09-23 | — | — | EP | disclosed |