Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700414 | 0.88 | MAPT (0.38) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL13700703 | 0.87 | MAPT (0.37) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL13700465 | 0.86 | CYP4A11 (0.43) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL13700530 | 0.85 | MAPT (0.38) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL13700485 | 0.85 | MAPT (0.38) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL13700473 | 0.85 | ALDH1A1 (0.36) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL13700442 | 0.85 | HSP90AA1 (0.37) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL13700470 | 0.85 | MAPT (0.46) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL13700464 | 0.85 | GAA (0.37) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL13700467 | 0.85 | ALDH1A1 (0.41) | MAPTKDM4EALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324399-B2 | Heat resistance improver and reversible thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-2103445-A1 | Heat resistance improver and reversible thermosensitive recording medium | Ricoh Company, Ltd. (JP) | 2009-09-23 | — | — | EP | disclosed |