SCHEMBL13699406

SCHEMBL13699406

N#Cc1ccc2nn(-c3cc(CO)ccc3O)nc2c1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
POLB P06746 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
MAPK1 P28482 1/20 0.46
HSD17B10 Q99714 1/20 0.46
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
RAB9A P51151 1/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TP53 P04637 1/20 0.38
THRB P10828 1/20 0.38
SRC P12931 1/20 0.35
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
CYP19A1 P11511 10/20 0.34
EGLN2 Q96KS0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30240912 0.80 NPC1 (0.61) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL76414 0.80 NPC1 (0.61) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL13700392 0.80 NPC1 (0.47) KDM4EALDH1A1POLBALOX15HSD17B10
SCHEMBL13699403 0.80 NPC1 (0.43) KDM4EHPGDALOX15HSD17B10NPC1
SCHEMBL5064193 0.78 KDM4E (0.40) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL13700388 0.77 NPC1 (0.43) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL25407160 0.77 KDM4E (0.41) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL29384272 0.77 KDM4E (0.41) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL5070150 0.77 TP53 (0.36) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL105876 0.77 KDM4E (0.41) KDM4EALDH1A1POLBHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2103445-B1 Heat resistance improver and reversible thermosensitive recording medium RICOH CO LTD (JP) 2015-05-06 EP disclosed
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
EP-2103445-A1 Heat resistance improver and reversible thermosensitive recording medium Ricoh Company, Ltd. (JP) 2009-09-23 EP disclosed