SCHEMBL105876

SCHEMBL105876

C=C(C)C(=O)OCCc1ccc(O)c(-n2nc3ccc(C#N)cc3n2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
POLB P06746 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TP53 P04637 2/20 0.36
THRB P10828 1/20 0.36
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
YWHAG P61981 1/20 0.33
APP P05067 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
USP14 P54578 1/20 0.32
CDK8 P49336 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384272 1.00 KDM4E (0.41) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL5064193 0.90 KDM4E (0.40) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL30038851 0.89 NPC1 (0.33) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL30039355 0.87 LMNA (0.36) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL7268063 0.86 NPC1 (0.46) KDM4EALDH1A1POLBHPGDTP53
SCHEMBL93485 0.86 NPC1 (0.47) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL29358846 0.86 NPC1 (0.47) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL25407160 0.85 KDM4E (0.41) KDM4EALDH1A1POLBHPGDALOX15
SCHEMBL105442 0.85 LMNA (0.35) KDM4EALDH1A1HPGDTP53THRB
SCHEMBL29384829 0.85 LMNA (0.35) KDM4EALDH1A1HPGDTP53THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479194-B2 Laminate TOYOBO CO., LTD. (JP) 2025-11-25 US disclosed
EP-4651688-A1 DEVICE AND METHOD FOR MANUFACTURING DEVICE Toyobo Co., Ltd. (JP) 2025-11-19 EP disclosed
WO-2025089524-A1 BLUE LIGHT SHIELDING FILM AND ELECTRONIC DEVICE COMPRISING SAME 도레이첨단소재 주식회사 2025-05-01 WO disclosed
WO-2024150811-A1 DEVICE AND METHOD FOR MANUFACTURING DEVICE 東洋紡株式会社 2024-07-18 WO disclosed
CN-116075368-B Resin composition, cured product, method for producing same, and laminate 三菱化学株式会社 2024-06-11 CN disclosed
CN-118119507-A Laminate of inorganic substrate with protective film and heat-resistant polymer film 东洋纺株式会社 2024-05-31 CN disclosed
CN-118076482-A Laminate with protective film-assisted release tape 东洋纺株式会社 2024-05-24 CN disclosed
EP-4360873-A1 LAMINATE TOYOBO CO., LTD. (JP) 2024-05-01 EP disclosed
US-20240075718-A1 LAMINATE TOYOBO CO., LTD. (JP) 2024-03-07 US disclosed
US-20240059057-A1 LAMINATED FILM, LAMINATED FILM MANUFACTURING METHOD, LAMINATE, AND LAMINATE MANUFACTURING METHOD TOYOBO CO., LTD. (JP) 2024-02-22 US disclosed
EP-1205498-A1 (Meth)acrylate ester-based resin composition Nippon Shokubai Co., Ltd. (JP) 2002-05-15 EP disclosed
US-20020045702-A1 (Meth)acrylate ester-based resin composition NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-18 US disclosed
US-6372355-B1 MINIMIZED COLORING OR DETERIORATION INDUCED BY ULTRAVIOLET RADIATION, WITH INTERLAYER ADHESION AND ABRASION RESISTANCE AND WEATHERABILITY NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-16 US disclosed
US-20020040094-A1 Resin composition for coating and coating composition for curing NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-04 US disclosed
EP-1184396-A1 (Meth)acrylate ester-based resin composition Nippon Shokubai Co., Ltd. (JP) 2002-03-06 EP disclosed
EP-1178080-A2 Curable resin coating composition Nippon Shokubai Co., Ltd. (JP) 2002-02-06 EP disclosed
US-6312802-B1 ADDITION POLYMERS OF 2,2,6,6-TETRAMETHYL-4-PIPERAZINYL ACRYLATES OR ACRYLAMIDES; ADDITION POLYMERS OF (BENZOTRIAZOL-2'-YL)HYDROXYPHENYL ACRYLATES NIPPON SHOKUBAI CO., LTD. (JP) 2001-11-06 US disclosed
US-6200686-B1 CURABLE MIXTURE OF A DICYCLOPENTENYL GROUP-CONTAINING UNSATURATED POLYESTER, UNSATURATED MONOMERS OF AN AROMATIC HYDROCARBON AND AN ALIPHATIC COMPOUND AND A SOLUBLE THERMO-PLASTIC POLYMER; LAMINATED OR JOINT MONOLITHIC MOLDING NIPPON SHOKUBAI CO., LTD. (JP) 2001-03-13 US disclosed
EP-1067223-A1 Polymers for imparting light resistance to fibers, highly light-resistant fibers, and process for producing the fibers NIPPON SHOKUBAI CO., LTD. (JP) 2001-01-10 EP disclosed
EP-1036834-A1 ULTRAVIOLET-ABSORBING LAMINATED RESINOUS MATERIAL Nippon Shokubai Co., Ltd. (JP) 2000-09-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020045702-A1 (Meth)acrylate ester-based resin composition MNAT1, MAT1A, COPE KDM4E 411/4885ALDH1A1 298/4885POLB 1565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.