SCHEMBL13699471

SCHEMBL13699471

Cc1cc(CCO)cc(-n2nc3ccc([N+](=O)[O-])cc3n2)c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
POLB P06746 3/20 0.46
TSHR P16473 1/20 0.43
TTR P02766 1/20 0.39
PPARG P37231 1/20 0.38
TXNRD1 Q16881 1/20 0.38
TXNRD3 Q86VQ6 1/20 0.38
TXNRD2 Q9NNW7 1/20 0.38
MAPT P10636 6/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
PKM P14618 2/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
THRB P10828 1/20 0.37
LMNA P02545 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13700723 0.86 MEN1 (0.49) MEN1KMT2APOLBTSHRPPARG
SCHEMBL13700431 0.86 MEN1 (0.47) MEN1KMT2APOLBTSHRPPARG
SCHEMBL13700422 0.86 MEN1 (0.47) MEN1KMT2APOLBTSHRPPARG
SCHEMBL13700474 0.85 MEN1 (0.48) MEN1KMT2APOLBTSHRPPARG
SCHEMBL13700492 0.84 MEN1 (0.47) MEN1KMT2APOLBTSHRTXNRD1
SCHEMBL13699442 0.82 MEN1 (0.65) MEN1KMT2APOLBTSHRTXNRD1
SCHEMBL13699490 0.82 KMT2A (0.45) MEN1KMT2APOLBTSHRPPARG
SCHEMBL13699452 0.82 PTGS2 (0.37) MEN1KMT2APOLBMAPTNPC1
SCHEMBL74479 0.81 NPC1 (0.50) MEN1KMT2APOLBPPARGMAPT
SCHEMBL30240966 0.81 NPC1 (0.50) MEN1KMT2APOLBPPARGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
EP-2103445-A1 Heat resistance improver and reversible thermosensitive recording medium Ricoh Company, Ltd. (JP) 2009-09-23 EP disclosed