Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 4/20 | 0.34 |
| ▸ | JAK1 | P23458 | 4/20 | 0.34 |
| ▸ | TYK2 | P29597 | 4/20 | 0.34 |
| ▸ | JAK3 | P52333 | 4/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699450 | 0.90 | KMT2A (0.41) | KMT2AMEN1NPC1LMNARAB9A | |
| SCHEMBL13700389 | 0.88 | MEN1 (0.41) | KMT2AMEN1NPC1LMNARAB9A | |
| SCHEMBL13700393 | 0.84 | CA12 (0.44) | KMT2AMEN1NPC1LMNARAB9A | |
| SCHEMBL13700394 | 0.83 | CA12 (0.50) | NPC1LMNARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL13699464 | 0.82 | MEN1 (0.37) | KMT2AMEN1NPC1LMNARAB9A | |
| SCHEMBL13700403 | 0.82 | TP53 (0.40) | KMT2AMEN1NPC1LMNARAB9A | |
| SCHEMBL13700398 | 0.81 | ALDH1A1 (0.48) | KMT2AMEN1NPC1LMNARAB9A | |
| SCHEMBL11608022 | 0.79 | NPC1 (0.58) | KMT2AMEN1NPC1LMNARAB9A | |
| SCHEMBL30240912 | 0.79 | NPC1 (0.61) | KMT2AMEN1NPC1LMNARAB9A | |
| SCHEMBL76414 | 0.79 | NPC1 (0.61) | KMT2AMEN1NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324399-B2 | Heat resistance improver and reversible thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-2103445-A1 | Heat resistance improver and reversible thermosensitive recording medium | Ricoh Company, Ltd. (JP) | 2009-09-23 | — | — | EP | disclosed |