Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700475 | 0.89 | KDM4E (0.40) | SIRT2MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13700477 | 0.85 | MAOB (0.41) | PTGS2MAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL13700478 | 0.85 | NPC1 (0.37) | SIRT2MAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL13700479 | 0.84 | PRMT5 (0.37) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL13699488 | 0.83 | CA2 (0.38) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL13700459 | 0.83 | POLB (0.35) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL13700476 | 0.82 | MAOB (0.46) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL13700483 | 0.82 | MEN1 (0.39) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL13700481 | 0.81 | GAA (0.44) | SIRT2MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13700516 | 0.80 | CYP1A1 (0.40) | NPC1RAB9ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324399-B2 | Heat resistance improver and reversible thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-2103445-A1 | Heat resistance improver and reversible thermosensitive recording medium | Ricoh Company, Ltd. (JP) | 2009-09-23 | — | — | EP | disclosed |