Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.35 |
| ▸ | IL1B | P01584 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1020147 | 0.92 | KDM4E (0.36) | CNR2CNR1P2RX7IL1B | |
| SCHEMBL1020840 | 0.91 | P2RX7 (0.41) | CNR2P2RX7IL1B | |
| SCHEMBL1019586 | 0.88 | MAP2K1 (0.39) | CNR2P2RX7IL1B | |
| SCHEMBL1019507 | 0.84 | P2RX7 (0.46) | CNR2P2RX7IL1B | |
| SCHEMBL1019695 | 0.82 | CNR2 (0.37) | CNR2CNR1P2RX7IL1B | |
| SCHEMBL1019517 | 0.82 | P2RX7 (0.39) | CNR2CNR1P2RX7IL1B | |
| SCHEMBL12955303 | 0.82 | P2RX7 (0.41) | CNR2P2RX7IL1B | |
| SCHEMBL1021504 | 0.81 | P2RX7 (0.40) | CNR2CNR1P2RX7IL1B | |
| SCHEMBL1019436 | 0.81 | CNR2 (0.39) | CNR2CNR1P2RX7IL1B | |
| SCHEMBL1019972 | 0.80 | CNR2 (0.46) | CNR2P2RX7IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2105164-A1 | Novel P2X7R antagonists and their use | Affectis Pharmaceuticals AG (DE) | 2009-09-30 | — | — | EP | disclosed |