SCHEMBL1370014

SCHEMBL1370014

C[N+](C)(C)CC(CC(O)CO)OP(=O)([O-])O

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
SLC22A16 Q86VW1 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 1/20 0.33
HRH1 P35367 1/20 0.33
CYP2C19 P33261 1/20 0.32
RECQL P46063 1/20 0.32
MAPT P10636 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5357430 0.89 SMN1; SMN2 (0.35) SMN1; SMN2
SCHEMBL10604508 0.87 SMN1; SMN2 (0.42) SMN1; SMN2SLC22A16MEN1KMT2ACYP1A2
SCHEMBL10606120 0.87 SMN1; SMN2 (0.42) SMN1; SMN2SLC22A16MEN1KMT2ACYP1A2
SCHEMBL10602657 0.87 SMN1; SMN2 (0.42) SMN1; SMN2SLC22A16MEN1KMT2ACYP1A2
Zinc Ion SCHEMBL10604220 0.87 SMN1; SMN2 (0.42) SMN1; SMN2SLC22A16MEN1KMT2ACYP1A2
SCHEMBL27282999 0.86 SMN1; SMN2 (0.37) SMN1; SMN2SLC22A16MEN1KMT2ACYP1A2
SCHEMBL14739090 0.79 MEN1 (0.35) SMN1; SMN2MEN1KMT2ACYP1A2HRH1
SCHEMBL8861292 0.79 SMN1; SMN2 (0.56) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL192296 0.79 MEN1 (0.39) SMN1; SMN2SLC22A16MEN1KMT2ACYP1A2
SCHEMBL5255308 0.78 MEN1 (0.34) SMN1; SMN2SLC22A16MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 626 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240156790-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2024-05-16 US claimed
US-20240115499-A1 DHA and Choline Emulsion CAPSUGEL BELGIUM NV (BE) 2024-04-11 US claimed
EP-4347605-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS The Trustees of Columbia University in the City of New York (US) 2024-04-10 EP claimed
EP-4319759-A1 1-METHYLXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF Ingenious Ingredients, LP (US) 2024-02-14 EP claimed
EP-4313056-A1 THE USE OF PARAXANTHINE TO IMPROVE PERFORMANCE IN VIDEO GAMERS PX ING, LLC (US) 2024-02-07 EP claimed
EP-4312801-A1 PARAXANTHINE-BASED COMPOSITIONS FOR PROMOTING WEIGHT LOSS PX ING, LLC (US) 2024-02-07 EP claimed
WO-2023173111-A2 INTRA-DOSAGE FORM COATINGS AND APPLICATIONS THEREOF BALCHEM CORPORATION (US) 2023-09-14 WO claimed
US-20230217977-A1 DIETARY CHOLINE SUPPLEMENTATION TO REDUCE TUMOR VOLUME AND ENHANCE COGNITIVE RESPONSE DURING CANCER TREATMENT NATIONAL INSTITUTES OF HEALTH 2023-07-13 US claimed
WO-2023064511-A9 PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF Ingenious Ingredients, LP (US) 2023-06-08 WO claimed
WO-2023084508-A1 COGNITIVE ENHANCING DIETARY SUPPLEMENT ZEEVI INON MOSHE (IL) 2023-05-19 WO claimed
US-20040043013-A1 Metabolic uncoupling therapy MCCLEARY EDWARD LARRY (US) 2004-03-04 US claimed
WO-2002013838-A1 SEAL-OIL-BASED PHARMACEUTICAL, COSMETIC, DERMO-COSMETIC, HYGIENE, ALIMENTARY AND PARA-ALIMENTARY (FOOD-SUPPLEMENTS) PRODUCTS; THEIR METHODS OF PREPARATION; THEIR USES AS PREVENTIVE AND/OR AS THERAPEUTIC AGENTS FUNDAÇAO ESSPRIT-ICARUS (FUNDAÇAO EUROPEIA DE INVESTIGAÇAO MEDICA), NGO; IPSS. (PT) 2002-02-21 WO claimed
US-5250719-A Process for the preparation of L-α-glycerylphosphoryl-choline and of L-α-glycerylphosphorylethanolamine PRIME EUROPEAN THERAPEUTICALS S.P.A. (IT) 1993-10-05 US claimed
EP-0217765-B1 PROCESS FOR THE PREPARATION OF L-ALPHA-GLYCERYLPHOSPHORYLCHOLINE, L-ALPHA-GLYCERYLPHOSPHORYLETHANOLAMINE FROM CRUDE AND/OR DEOLEATED LECITHINS ISTITUTO CHEMIOTERAPICO ITALIANO FINE CHEMICALS S.p.A. (IT) 1990-08-16 EP claimed
EP-0186803-B1 DIACYLDERIVATIVES OF GLYCERYLPHOSPHORYLCHOLINE HAVING THERAPEUTICAL ACTIVITY, A PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS NEOPHARMED S.p.A. (IT) 1989-09-20 EP claimed
US-4824978-A Complexes of glycerylphosphorylcholine NEOPHARMED SPA (IT) 1989-04-25 US claimed
US-4699901-A Diacyl derivatives of glycerylphosphorylcholine, their preparation, and antihyperlipidemic compositions NEOPHARMED SPA (IT) 1987-10-13 US claimed
EP-0217765-A2 Process for the preparation of L-alpha-glycerylphosphorylcholine, L-alpha-glycerylphosphorylethanolamine from crude and/or deoleated lecithins ISTITUTO CHEMIOTERAPICO ITALIANO FINE CHEMICALS S.p.A. (IT) 1987-04-08 EP claimed
EP-0186803-A2 Diacylderivatives of glycerylphosphorylcholine having therapeutical activity, a process for their preparation and related pharmaceutical compositions NEOPHARMED S.p.A. (IT) 1986-07-09 EP claimed
US-4130571-A Process for preparing 1,2-diacyl-3-glycerylphosphorylcholines NIPPON SHOJI KAISHA, LTD. (JP) 1978-12-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240156790-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS AIFM2, GPX1, SLC7A11 SMN1; SMN2 311/4885SLC22A16 433/4885MEN1 2584/4885
US-20240115499-A1 DHA and Choline Emulsion LIPA, CHAT, PHOSPHO1 SMN1; SMN2 863/4885SLC22A16 864/4885MEN1 2703/4885
US-20230217977-A1 DIETARY CHOLINE SUPPLEMENTATION TO REDUCE TUMOR VOLUME AND ENHANCE COGNITIVE RESPONSE DURING CANCER TREATMENT CHAT, CHKA, CHKB SMN1; SMN2 2084/4885SLC22A16 1592/4885MEN1 218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.