AIFM2

Ferroptosis suppressor protein 1 · Q9BRQ8 · AIFM2 on Sugi Atlas →

0 patent compounds predicted against AIFM2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to AIFM2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer PHASE4UNKNOWN
Enhancing Effect on Tumour Apoptosis With the Use of Pentoxifylline in Patients With Hodgkin Lymphoma PHASE4UNKNOWN
Effect of Pioglitazone Administered to Patients With Friedreich's Ataxia: Proof of Concept PHASE3COMPLETED
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma PHASE2COMPLETED
IFNα Expressing Mesenchymal Stromal Cells for Locally Advanced/Metastatic Solid Tumors PHASE1/PHASE2RECRUITING
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
Simvastatin in Secondary Progressive Multiple Sclerosis PHASE2COMPLETED
Clinical Effects of Alpha-Lipoic Acid in Advanced NSCLC PHASE2NOT_YET_RECRUITING
Labile Iron Removal by Adding the Iron Chelator MEX-CD1 to Dialysate in Sepsis-Associated Acute Kidney Injury PHASE1/PHASE2RECRUITING
A Phase I Study Of Thymoglobulin In Patients With Relapsed Or Refractory Multiple Myeloma PHASE1COMPLETED
A Clinical Study to Evaluate the Safety of MF1, a New Treatment for Parkinson's Disease-related Disorders (MF1 Study) PHASE1RECRUITING
Methylprednisolone Treatment of Friedreich Ataxia EARLY_PHASE1COMPLETED
Apoptosis Markers in Aggressive Periodontitis nanCOMPLETED
Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis nanNOT_YET_RECRUITING
Identification of Serum Level of Glutathione Peroxidase 4 nanNOT_YET_RECRUITING
Prognostic Value of (DHODH) Expression in (HGSOC): A Comparative Study Between Neoadjuvant and Adjuvant Chemotherapy Settings nanNOT_YET_RECRUITING
Natural History Study of FDXR Mutation-related Mitochondriopathy nanCOMPLETED
Ferroptosis Role in the Pathophysiology of Systemic Lupus Erythematosus nanRECRUITING
Evaluation of Serum Gasdermin D Level As a Potential Biomarker of Disease Activity in Vitiligo Patients nanUNKNOWN
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy nanCOMPLETED
Impact of CASP3 Gene in Chemoresistance nanNOT_YET_RECRUITING
Skeletal Muscle Apoptosis and Physical Performance; Oxidative RNA/DNA Damage and Repair in Aged Human Muscle nanCOMPLETED
Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells nanRECRUITING
Serum NGAL IN Patients With Multiple Myeloma nanUNKNOWN
LIPCAR, Cuproptosis, and Α-SMA in the Pathogenesis of AMI and Remodeling nanNOT_YET_RECRUITING
Autophagy/Apoptosis Balance in Placental Vascular Pathologies nanRECRUITING
Meat-based Versus Pesco-vegetarian Diet and Colorectal Cancer nanCOMPLETED
Translating Single-cell Vulnerability Into Novel ALS Biomarkers and Therapeutic Targets: Towards a Liquid Nerve Biopsy nanRECRUITING
The Relationship Between Homocysteine and Manifestation of Parkinson's Disease Patients nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a AIFM2 binder may also engage these)

ProteinNameSimilarity
A5PJM4 1.000 A5PJM4 →
B5FXE5 0.995 B5FXE5 →
Q8BUE4 0.994 Q8BUE4 →
E1BR24 0.992 E1BR24 →
B4F6I3 0.977 B4F6I3 →
Q6GLW8 0.972 Q6GLW8 →
Q3TMV7 0.965 Q3TMV7 →
Q6PBT5 0.961 Q6PBT5 →
Q922Z0 0.960 Q922Z0 →
Q5REJ2 0.959 Q5REJ2 →
Q96NN9 0.958 Q96NN9 →
Q8WU10 0.958 Q8WU10 →
SQOR Sulfide:quinone oxidoreductase, mitochondrial 0.955 landscape →
A7YVH9 0.955 A7YVH9 →
Q3TY86 0.955 Q3TY86 →
O54695 0.954 O54695 →
Q68FS6 0.954 Q68FS6 →
Q9D665 0.951 Q9D665 →
P24815 0.951 P24815 →
P31754 0.950 P31754 →
P31228 0.950 P31228 →
DDO D-aspartate oxidase 0.950 landscape →
O88736 0.950 O88736 →
Q9SVU0 0.950 Q9SVU0 →
P20132 0.949 P20132 →
P13439 0.949 P13439 →
D4A2H2 0.949 D4A2H2 →
Q62904 0.949 Q62904 →
P09367 0.948 P09367 →
Q64421 0.948 Q64421 →