Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10868651 | 0.85 | PLA2G1B (0.32) | — | |
| SCHEMBL14931565 | 0.76 | — | — | |
| SCHEMBL5158425 | 0.76 | — | — | |
| SCHEMBL28661962 | 0.76 | — | — | |
| SCHEMBL7791100 | 0.75 | — | — | |
| SCHEMBL7528385 | 0.74 | KDM4E (0.50) | KDM4EL3MBTL1MAPT | |
| SCHEMBL1274023 | 0.72 | PLA2G1B (0.41) | — | |
| SCHEMBL19509739 | 0.71 | TSHR (0.34) | — | |
| SCHEMBL5148049 | 0.70 | KDM4E (0.60) | KDM4EL3MBTL1MAPT | |
| SCHEMBL4503959 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109973-A2 | COMPOUNDS AND METHODS OF TREATING OBESITY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2009-09-11 | — | — | WO | disclosed |